Abe is the first primary protagonist in the Oddworld franchise, the titular protagonist of Abe's Oddysee, New 'n' Tasty, Abe's Exoddus, Soulstorm and the deuteragonist of Munch's Oddysee. He is a Mudokon, the native race of the continent Mudos. He is recognized by his species as the Messiah of the Mudokons. Despite Abe's skepticism in being the 'chosen one', Abe managed to liberate a large portion of his species from Glukkon oppression. He is also known for liberating any form of life that is being oppressed by unethical businesses such as the Vykkers of Vykker's Labs.
Abe began his life, as most slave Mudokons did, in an industrial establishment. Specifically, RuptureFarms, the biggest meat processing plant on Oddworld. Abe grew up more or less satisfied with the way things were, until he discovered the Glukkons in charge of RuptureFarms were faced with rapidly declining sales and planned to use Mudokons as a new kind of meat product. Horrified, Abe attempted to somehow escape from RuptureFarms, hoping to try and save his fellow Mudokon workers along the way. During his escape, Abe discovered his inherent ability to possess other beings and take full control over their bodies. Using this new power to his advantage, Abe was able to free himself from RuptureFarms.
Abe soon learned of an aspect of Oddworld with which he was completely unfamiliar; the native side. He learned of the way things used to be, and was directed by Big Face, the Shaman Mudokon, to the harsh regions of Paramonia and Scrabania, where he faced the sacred Paramites and Scrabs.
Surviving these trials, Abe was endowed with two mystical tattoos, one on each hand. They granted him the power to channel an ancient Mudokon God, the Shrykull. With this power, Abe returned to RuptureFarms, rescued all 99 Mudokon workers, and destroyed the factory before being rescued by Big Face.
After the celebration with 300 other Mudokons in the Monsaic Sanctum, the former Rupture Farms employees moved into to an outer section of the Monsaic Lines, cheering to Abe for rescuing them. A Masked Shaman had a meeting with Abe trying to encourage him to cut his stiches, with Abe refusing due to them being his only connection to his mother. The shaman warned of the fact that Abe's journey was far from over, stating that he was safe, "only for this moment. And this moment is over." As he said this, Necrum mines Sligs who were looking for a messanger that had escaped Necrum mines discovered the greater prize of an entire refuge of Mudokons, and started burning the cave. Abe was forced to flee the Raid on Monsaic along with his followers. On the outskirts of the cave Abe discovered the messenger that the Sligs were originally chasing. Abe tries to comfort the dying Mudokon, who was too close to death's door to recognise him by sight. He does recognise Abe by feeling the stiches on Abe's face, and warns him that Abe's followers are dying, and how he needs to find the keeper, but dies before informing Abe on why the Rupture Farms escapees are dying. Abe takes the map and amulet that the messenger was carrying, and runs outside into Gorge. He quickly discovers that Molluck has returned to kill Abe and restore his honour after the destruction of Rupture Farms. While Abe was able to meet up and ensure safety for his followers, Molluck destroys the bridge that would allow Abe to join them. Alf tells Abe that his followers can use the mineshaft to take a shortcut to Old Trellis, but Abe must take the long way through Sorrow Valley and to a Phatoline Station, where the train tracks would lead Abe to Old Trellis.
Abe escapes a trap Molluck set up for him as leaves for the abandoned mining facility at Sorrow Valley. There Abe finds some other escapees who were deadly sick from an unknown affliction. Abe finds ingredients throughout the caves that could make up an Antidote that cures them. Later on in Sorrow Valley, Abe find an already dead escapees with a message telling anyone who reads it to take on his journey to bring a tape labelled 'Projekt Soulstorm' to Abe. Abe pockets this tape and evades another trap from Molluck to make it to the Flub Fuels facility, Phat Station, where a train has pulled in. Abe manages to to get to the the train and proceeds to hijack it, forcing it to stop at Old Trellis. Abe re-unites with his followers, where he has a chat with Alf about the messenger, the tape and sick Mudokons. The amulet reveals that the Keeper is in Necrum. Abe takes a stop at Slig Barracks in order to watch the tape and to deactivate the Comms Tower to prevent any other factory from knowing about his escapades. The tape reveals that Soulstorm Brew will kill anyone who has drank it 48 hours after their previous drink if they do not drink it again.
Abe then infiltrates the depths of Necrum where he finds the Keeper, who informs him that the Keepers of the Necrum Sanctum exist to preserve Mudokon history in spite of the Glukkons. An alter in the Sanctum gives Abe his chest scar, knowledge of the true history of the Mudokons and the ability to use the Shrykull once again. Abe learns that the best way to free the Mudokons from Soulstorm Brew is to mix in the Antidote in a great enough quantity that the pipelines that bring the Brew from the brewery to all other factories would bring all Mudokons the antidote. Abe collects the antidote ingredients from the Feeco Deepot yards and infiltrates Soulstorm Brewery to bring the antidote to the whole continent, allowing Mudokons to rebel without the threat of cardio-vascualar failure. As Abe sits with Alf and Toby, he reveals that all Mudokons have the same mother, Sam, and that she is in Nolybab.